Vaccines have long been a valuable weapon in the fight against infectious illnesses. Vaccine research has surged in recent years, providing protection against a wide range of infectious illnesses. It has had a significant influence on the control and prevention of many infectious illnesses; however, some parents refuse to vaccinate their children. Although there is no federal law mandating children to be vaccinated, when they enroll in public schools, they must produce evidence of vaccines or, in certain states, paperwork allowing them to have a religious, personal, or philosophical objection to vaccinations. Vaccine exemptions are now permitted in all states. As a result, the federal government should be allowed to refuse entry to public school to children who are unvaccinated for non-medical reasons, as this would send a strong message that lowering barriers to vaccination and emphasizing the importance of high vaccination rates to protect the health of children attending school may encourage reluctant parents to vaccinate their children.